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Wolfgang Kreis Selected Research

Digitoxigenin

1/2020Investigation of the cytotoxic activity of two novel digitoxigenin analogues on H460 lung cancer cells.
11/2018Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+-ATPase inhibition.
2/2017A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines.
10/2015The New Semisynthetic Cardenolide Analog 3β-[2-(1-Amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) Efficiently Suppresses Cell Growth in Human Leukemia and Urological Tumor Cell Lines.

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Wolfgang Kreis Research Topics

Disease

10Neoplasms (Cancer)
04/2021 - 09/2014
5Lung Neoplasms (Lung Cancer)
04/2021 - 06/2016
5Heart Failure
06/2020 - 10/2011
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2021 - 04/2017
3Heart Diseases (Heart Disease)
01/2020 - 01/2018
3Prostatic Neoplasms (Prostate Cancer)
11/2018 - 10/2015
3Renal Cell Carcinoma (Grawitz Tumor)
08/2017 - 10/2015
1Human Influenza (Influenza)
10/2020
1Carcinoma (Carcinomatosis)
11/2018
1Cardiovascular Diseases (Cardiovascular Disease)
02/2017
1Neoplasm Metastasis (Metastasis)
06/2016
1Leukemia
10/2015
1Urologic Neoplasms (Urological Cancer)
10/2015
1Type 1 Spherocytosis
02/2006

Drug/Important Bio-Agent (IBA)

9Cardiac GlycosidesIBA
06/2020 - 10/2011
8CardenolidesIBA
04/2021 - 10/2015
5Adenosine Triphosphatases (ATPase)IBA
04/2021 - 04/2017
4DigitoxigeninIBA
01/2020 - 10/2015
3glucoevatromonosideIBA
04/2021 - 08/2017
3Pharmaceutical PreparationsIBA
04/2021 - 01/2018
33- (2- (1- amantadine)- 1- one- ethylamine)digitoxigeninIBA
11/2018 - 10/2015
3DigitoxinFDA Link
02/2017 - 10/2011
2Antiviral Agents (Antivirals)IBA
10/2020 - 04/2019
2LigandsIBA
01/2018 - 10/2011
2digitoxigenin monodigitoxosideIBA
01/2018 - 06/2016
2convallatoxinIBA
04/2017 - 06/2016
2Amantadine (Aman)FDA LinkGeneric
02/2017 - 10/2015
2ethylamineIBA
02/2017 - 10/2015
2Vinblastine (Vinblastine Sulfate)FDA Link
01/2015 - 09/2014
2Secologanin Tryptamine Alkaloids (Alseroxylon)FDA Link
01/2015 - 09/2014
2Vincristine (Oncovin)FDA LinkGeneric
01/2015 - 09/2014
1Ion Channels (Ion Channel)IBA
04/2021
1Paclitaxel (Taxol)FDA LinkGeneric
04/2019
1Hormones (Hormone)IBA
11/2018
1SurvivinIBA
11/2018
1Docetaxel (Taxotere)FDA Link
11/2018
1AndrogensIBA
11/2018
1Cyclin B1IBA
11/2018
1Cytostatic AgentsIBA
01/2018
1MicroRNAs (MicroRNA)IBA
02/2017
1Sodium-Potassium-Exchanging ATPase (Sodium, Potassium ATPase)IBA
10/2011
1Digoxin (Digitek)FDA LinkGeneric
10/2011
1galantide (M 15)IBA
02/2006

Therapy/Procedure

4Therapeutics
04/2021 - 10/2015
1Drug Therapy (Chemotherapy)
04/2021